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Cancer, Stroke and Diabetes in USA – Environment versus Genetics
Cancer, stroke and diabetes are the three major causes of death in USA, and as a result, the government spends humongous amount of research money to figure out the root causes of those diseases. Our...
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Battle over #GWAS: Ken Weiss Edition
The battle over #GWAS continues, thus providing us with more opportunity to learn. Today’s finding is one of the best. Thanks to @dgmacarthur, we discovered the blog of professor Ken Weiss ! The blog...
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Study History and Read Papers Written by ‘Dinosaurs’ (#GWAS)
Source: Ray Dailo ————————————- Huge amount of money gets spent on genome wide association studies (#GWAS) with the promises that they will lead to finding cures of complex diseases, but how good are...
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New AJHG Paper: ‘Born Again’ Dinosaurs Question Effectiveness of #GWAS
This paper could not have come at a worst time for BioMickWatson, who was about to classify us as dinosaurs for asking questions about the fast-rising (and soon to be obsolete) religion of Genome-wide...
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Ted Talk by Ben Goldacre on Manipulation of Clinical Trials
In “The Drugs Don’t Work”, but Open Publication Will Not Fix Them, we wrote about an informative book titled ‘Bad Pharma: How Drug Companies Mislead Doctors and Harm Patients’ by Ben Goldacre. Readers...
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Today’s Dinosaur Stories
A Complex World – Bill Bonner “Howard, I couldn’t figure out how to turn it off. All I got was menu after menu. But there’s no off switch.” Today’s beef is with today’s world. It is a world of so many...
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Universal Gate in Electronic Circuit What role does a single gene play in the bigger picture of defining traits? We will first present a conceptual idea from electrical engineering and then discuss...
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What Do Government-funded #GWAS Scientists Spend Most Time on?
When they are not complaining about sequester, they work on serious problems hurting our society. One such problem was detected on Sept 2. Apparently the wikipedia page of a scientist was ‘inflated’....
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Sequence Your Narcissome with 23 and Me
1. Single author paper – ‘I’ or ‘We’? Few weeks back, we asked: Single Author Bioinformatics Paper – ‘I’ or ‘We’? Almost all readers recommended ‘I’ and nobody said ‘we’, although we presume Heng Li...
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A Video Dedicated to #ENCODE, #GWAS and Other Government-funded ‘Big Science’...
Michael Schatz mentioned that ENCODE leader Mike Snyder will be presenting at the #GI2013 meeting, but his name is nowhere in the list of presenters. Have no worry !! Through our NSA and other spying...
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Big Data – Where Increasing Sample Size Adds More Errors
Conventional wisdom says larger sample size will make experiments more accurate, but that does not work in many situations. More samples can result in more errors, as explained by the following...
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The Rise and Fall of Human Genetics and the Common Variant – Common Disease...
Orli Bahcall (@obahcall), who is a Senior Editor of Nature Genetics, posted the following chart on success of GWAS. Nature Genetics is a ‘high-impact’ vanity journal, which should be renamed Nature...
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A Free Market Approach to Improving Human Health
In USA, cockroaches (also known as politicians) built a giant website to improve the health of the people. The website costs at least $600 million, contains 500 million lines of code and often fails to...
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Cancer: Story of a Real Patient
A large number of papers get published on cancer cell-lines, cancer GWAS, cancer microarray analysis and so on. Doing research on cancer is quite lucrative for the researchers, who made their...
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